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Seasonale
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Ethinyl estradiol and levonorgestrel are hormones
that affect the ovulatory and menstrual cycle of women.
Ethinyl estradiol and levonorgestrel prevent ovulation
(the release of an egg from an ovary), therefore
preventing the possibility of pregnancy. Seasonale may
also inhibit pregnancy by causing the cervical mucous to
thicken, which makes it harder for sperm to move toward
the uterus, and reducing the likelihood of attachment of
a fertilized egg to the uterus.
Important Warning:
Cigarette smoking increases
the risk of serious side effects from Seasonale,
including heart attacks, blood clots, and strokes. This
risk is higher for women over 35 years old and heavy
smokers (15 or more cigarettes per day). If you take
Seasonale, you should not smoke.
Medication Information
Seasonale is used to
prevent pregnancy. Estrogen and progestin are two female
sex hormones. Combinations of estrogen and progestin
work by preventing the release of eggs from the ovaries
(ovulation) and changing the cervical mucus and the
lining of the uterus. Seasonale is a very effective
method of birth control, but they do not prevent the
spread of AIDS and other sexually transmitted diseases.
How should Seasonale be used?
Seasonale come in
packets of 21 or 28 tablets to take by mouth once a day.
To avoid upset stomach, take Seasonale with food or
milk. Take the tablet routinely at the same time every
day (e.g., after dinner or at bedtime) to help you
remember to take the tablet regularly. Missing doses
increases your risk of becoming pregnant.
When first starting on Seasonale, use an additional
method of birth control until you have correctly taken 7
days' worth of medicine.
If you have a 21-tablet packet, take one tablet daily
for 21 days and then none for seven days. Then start a
new packet.
If you have a 28-tablet packet, take one tablet daily
for 28 days. The last seven tablets are a different
color. These tablets are not birth-control pills; they
contain iron (ferrous fumarate) or an inactive
ingredient. You should take one tablet daily
continuously for 28 days in the order specified in your
packet, starting a new packet the day after taking your
28th tablet.
Follow the directions on your prescription label
carefully concerning when to take your first tablet (on
the first or fifth day of your menstrual period or on
the first Sunday after or on which bleeding begins).
Take the oral contraceptive exactly as directed. Do not
take more or less of it or take it more often than
prescribed by your doctor. Do not stop taking Seasonale
without talking to your doctor.
If you have recently given birth, wait until 4 weeks
after giving birth to begin taking Seasonale.
Before taking Seasonale, ask your pharmacist or
doctor for a copy of the manufacturer's information for
the patient and read it carefully.
Other uses for Seasonale Seasonale may be prescribed
for other uses; ask your doctor or pharmacist for more
information.
What special precautions should I follow?
Before taking Seasonale,
- tell your doctor and pharmacist if you are
allergic to estrogen, progestin, or any other
medications.
- tell your doctor and pharmacist what prescription
and nonprescription medications, vitamins, and
nutritional supplements you are taking. Be sure to
mention any of the following: acetaminophen (APAP,
Tylenol); antibiotics; anticoagulants ('blood
thinners') such as warfarin (Coumadin); atorvastatin
(Lipitor); clofibrate (Atromid-S); cyclosporine
(Neoral, Sandimmune); griseofulvin (Fulvicin,
Grifulvin, Grisactin); HIV protease inhibitors such as
indinavir (Crixivan) and ritonavir (Norvir);
medications for seizures such as carbamazepine
(Tegretol), phenobarbital (Luminal, Solfoton),
phenytoin (Dilantin), and topiramate (Topamax);
morphine (Kadian, MS Contin, MSIR, others); oral
steroids such as dexamethasone (Decadron, Dexone),
methylprednisolone (Medrol), prednisone (Deltasone),
and prednisolone (Prelone); phenylbutazone; rifabutin
(Mycobutin); rifampin (Rifadin, Rimactane); temazepam
(Restoril); theophylline (Theobid, Theo-Dur); and
thyroid medication such as levothyroxine (Levothroid,
Levoxyl, Synthroid). Before taking Yasmin, tell your
doctor and pharmacist if you are taking
angiotensin-converting enzyme (ACE) inhibitors such as
benazepril (Lotensin), enalapril (Vasotec), and
lisinopril (Prinivil, Zestril); angiotensin II
antagonists such as irbesartan (Avapro), losartan
(Cozaar), and valsartan (Diovan); aspirin and other
nonsteroidal anti-inflammatory medications (NSAIDS)
such as ibuprofen (Advil, Motrin) and naproxen (Aleve,
Naprosyn); diuretics ('water pills') such as amiloride
(Midamor), spironolactone (Aldactone), and triamterene
(Dyrenium); or heparin. Your doctor may need to change
the doses of your medications or monitor you carefully
for side effects.
- tell your doctor what herbal products you are
taking, especially St. John's wort.
- tell your doctor if you have or have ever had
breast lumps or cancer; endometrial cancer; high blood
pressure; high blood cholesterol and fats; diabetes
(high blood sugar); asthma; stroke; blood clots;
toxemia (high blood pressure during pregnancy); heart
attack; epilepsy (seizures); migraine headaches;
depression; liver, heart, gallbladder, or kidney
disease; adrenal insufficiency (for Yasmin); jaundice
(yellowing of the skin or eyes); vaginal bleeding
between menstrual periods; and excessive weight gain
and fluid retention (bloating) during the menstrual
cycle.
- do not take Seasonale if you are pregnant, plan to
become pregnant, or are breast-feeding. If you become
pregnant while taking Seasonale, call your doctor
immediately.
- if you are having surgery, including dental
surgery, tell the doctor or dentist that you are
taking Seasonale.
- tell your doctor and pharmacist if you wear
contact lenses. If you notice changes in vision or
ability to wear your lenses while taking hormone
replacement therapy, see an eye doctor.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue
your normal diet.
What should I do if I forget a dose?
If you miss
doses of your oral contraceptive, you may be at risk for
becoming pregnant. Instructions about missed doses are
different for different products. Carefully read the
instructions in the manufacturer's information for the
patient. If you have any questions, call your doctor or
pharmacist. If you miss pills, you may need to use a
backup method of birth control for 7 days or until the
end of the cycle.
What side effects can Seasonale cause?
Seasonale may cause side effects. Tell your doctor
if any of these symptoms are severe or do not go away:
- upset stomach
- vomiting
- stomach cramps or bloating
- diarrhea
- constipation
- gingivitis (swelling of the gum tissue)
- weight gain or weight loss
- brown or black skin patches
- acne
- swelling of the hands, feet, or lower legs (fluid
retention)
- hair growth in unusual places
- bleeding or spotting between menstrual periods
- changes in menstrual flow
- painful or missed periods
- breast tenderness, enlargement, or discharge
- difficulty wearing contact lenses
Some side effects can be seious. The following
symptoms are uncommon, but if you experience any of
them, call your doctor immediately:
- severe headache
- shortness of breath
- severe vomiting
- partial or complete loss of vision
- double vision
- speech problems
- dizziness or faintness
- weakness or numbness of an arm or leg
- crushing chest pain or chest heaviness
- coughing up blood
- calf pain
- severe stomach pain
- yellowing of the skin or eyes
- severe depression
- unusual bleeding
- loss of appetite
- extreme tiredness, weakness, or lack of energy
- fever
- dark-colored urine
- light-colored stool
- rash
Seasonale may increase the risk of developing
endometrial and breast cancer, gallbladder disease,
liver tumors, heart attack, stroke, and blood clots.
Talk to your doctor about the risks of taking Seasonale.
Seasonale may cause other side effects. Call your
doctor if you have any unusual problems while taking
Seasonale.
What storage conditions are needed for
Seasonale?
Keep Seasonale in the packet it came in,
tightly closed, and out of reach of children. Store it
at room temperature and away from excess heat and
moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Talk to
your pharmacist about the proper disposal of your
medication.
In case of emergency/overdose
In case of
overdose, call your local poison control center at
1-800-222-1222. If the victim has collapsed or is not
breathing, call local emergency services at 911.
What other information should I know?
Keep all
appointments with your doctor and the laboratory. You
should have a complete physical examination every year,
including blood pressure measurements, breast and pelvic
exams, and a Pap test. Follow your doctor's directions
for examining your breasts; report any lumps
immediately.
Before you have any laboratory tests, tell the
laboratory personnel that you take Seasonale, as
Seasonale may interfere with some laboratory tests.
If you miss one menstrual period and have taken your
tablets as directed, continue taking them. However, if
you miss one period and have not taken your tablets as
directed or if you miss two menstrual periods and have
taken the tablets as directed, call your doctor and use
another method of birth control until you have a
pregnancy test.
If you wish to stop taking Seasonale and become
pregnant, use another method of birth control for at
least 3 months after you stop taking the tablets to be
sure that the medication will not harm the fetus. It may
take a long time for you to become pregnant after you
stop taking Seasonale, especially if you have never had
a baby or if you had irregular, infrequent, or complete
absence of menstrual periods before taking Seasonale.
Questions should be discussed with your doctor.
Do not let anyone else take your medication. Ask your
pharmacist any questions you have about refilling your
prescription. |